Truly All-Atom Boltzmann sampling with AquaGen

We built a model that shows it’s possible to train a Boltzmann sampler that still works with a key ingredient of biochemical molecular dynamics: water.

Jul 1 • Emmanuel Bengio and Sanjeev Raja

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June 2026

f-Trajectory Balance: a loss family that enables exploration in molecule generation, LLMs and generative models

Connect with us: Valence is constantly seeking talented individuals with diverse backgrounds and expertise to join our team.

Jun 19 • Jason Hartford

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May 2026

Grounding Perturbation Prediction in Biological Knowledge

Decoding Transcriptomics Responses with TxPert

May 4 • Ihab

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April 2026

Towards Reasoning in Virtual Cells

Bridging predict and discover with autonomous mechanistic explanations

Apr 16 • Yunhui Jang, Lu Zhu, and Emmanuel

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Building the Virtual Protein

Escaping the Molecular Dynamics Bottleneck

Apr 14 • Cristian Gabellini and Francesco Di Giovanni

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Virtual Cells for Microscopy Assays

Overcoming the physical constraints of the lab

Apr 1 • Jason Hartford, Emmanuel, and Therence

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March 2026

The Virtual Cell Comeback

An introduction to simulating biology

Mar 24 • Cas, Emmanuel, and Therence

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